### Topics for 2015 Fall Session | Syllabi Statements

Website: OpenMx
Text: Methodology for Genetic Studies of Twins and Families by Neale & Cardon, 1992 revision PDF of Neale & Maes book.

Date Lecture Topic Lecturer Notes and Examples
Aug 25 Intro Genetic Epidemiology Biometrical Genetics Path Analysis Matrix Algebra Introduction of the Documentation Matrix Algebra Script
Algebra Exercise
New Beginners Guide Script
Alternative Approaches Script
Sep 01 Summarizing Data, Testing Model Assumptions, Fitting Twin Models Summarizing Data & Fitting Twin Models Univariate Twin Saturated Continuous Univariate Twin Saturated+Twin Continuous
Sep 08 Summarizing Data, Testing Model Assumptions, Fitting Twin Models to Ordinal Data Threshold Models Summarizing Data & Fitting Twin Models to Ordinal Data Univariate Twin Saturated Binary Univariate Twin Saturated Ordinal Univariate Twin ACE Binary Univariate Twin ACE Binary + Submodels Univariate Twin ACE Ordinal
Sep 15 Heterogeneity, Gene X Sex Interaction Heterogeneity Models Univariate Twin Heterogeneity ADE Univariate Twin Heterogeneity ACE Univariate Twin Heterogeneity ACE 5 groups rg Univariate Twin Heterogeneity ACE 5 groups rc
Sep 29 Gene X Environment Interaction GxE Interaction Models Univariate Moderated ACE 1 moderator Univariate Moderated ACE 2 moderators Bivariate Moderated ACE
Oct 13 Bivariate Genetic Analysis Bivariate Genetic Models Bivariate ACE
Oct 20 Multivariate Genetic Analysis Multivariate Models Twin Multivariate Continuous usski.rec
Nov 10 Power & Simulation Power & Simulation simMeanEst.R simNormDist.R powerApproximation.R testSimC.R runSimC.R
Nov 17 Extended Pedigrees Extended Twin Design twUniAceOrds.R twUniAceTOrds.R twpaUniAeOrds.R twpaUniAceOrds.R twpaUniAcefOrdsSH.R twpaUniAcefOrdsPA.R twpaUniAceiOrdsPA.R chatt4tp.ord
Nov 24 Longitudinal Genetic Analysis Developmental Genetic Analysis twinDevAceCon.R jepq.txt
Dec 01 Linkage and Association Linkage and Association Analysis twinAqeCon.R twinAqegCon.R lipidsIBD.dat
Helper Docs Gen Epi Helper Functions
Literature N&C92: Scope of Genetic Analysis N&C92: Biometrical Genetics Eaves et al 2005 Maes 2005 Neale et al 2009 Boomsma et al 2002 Posthuma et al 2003 vanDongen et al 2012