Dr. Vladimir I. Vladimirov’s Lab focuses on the molecular (i.e. gene expression, miRNA and epigentics) and cellular mechanisms underlying the etiology of schizophrenia and bipolar disorders and addiction phenotypes (i.e. alcohol dependence). Dr. Vladimirov’s lab houses 300 postmortem brain collected from subjects with schizophrenia and bipolar disorder, alcohol dependence and normal controls.
Tissue Culture Room
Dr. Vladimirov’s lab is equipped with a fully functioning tissue culture laboratory, which is equipped with a cell culture laminar, a cell and tissue incubator and one fluorescent microscope (with magnifications of x10; x20, x40, x100).
Dr. Vladimirov’s main laboratory is equipped with a real-time PCR machine with an interchangeable thermal blocks suited for conducting 96 and 384 PCR reactions in parallel, 2 electrophoreses tanks for a protein based separation; 2 electrophoreses tanks agarose based DNA and RNA separation, 2 digitally controlled thermal baths and 2 thermal shakers, 2 large and 2 small refrigerators, two large freezers and one deep (-80°C) freezer.
The laboratory is equipped with 4 personal PC computers and one server.
The clinical resources in Vladimirov’s lab allow for performing intravenous alcohol infusions in healthy subjects. We house two digital pumps and two laptops with a software installed to initiate, control and maintain the alcohol infusions.