Research

Dr. Vladimirov Receives $400K Alcohol Dependence Grant

Vladimir Vladimirov, M.D., Ph.D., was awarded a two-year grant from the National Institute of Alcohol Abuse and Alcoholism in the amount of $419,375 to study the genome-wide expression patterns of genes and miRNA in the nucleus accumbens and prefrontal cortex from subjects with alcohol dependence (AD) and healthy controls. The award has two main goals: i) identify AD-relevant gene and miRNA networks and ii) detect genetic polymorphisms found to be ...

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VCU researchers and international partners first to identify shared risk genes for anxiety disorders

In the largest and most comprehensive study of its kind, researchers have successfully identified two novel genetic variants that could increase risk for the five primary anxiety disorders. The findings are the result of an international collaboration among 34 researchers from Virginia Commonwealth University and throughout academic institutions in the United States, Europe and Australia.

The international research team looked at genetic risk factors that are common across the five primary anxiety disorders identified in the fifth edition ...

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Student researches ‘subtle biological differences’ of addiction

Binge drinking is a growing problem in the United States, but are all problem drinkers the same? That is a question Virginia Commonwealth University student Megan Cooke hopes to answer.

Cooke has been interested in alcohol dependence and alcohol use behavior since receiving a postbaccalaureate Intramural Research Training Award to work at the National Institute on Alcohol Abuse and Alcoholism. She quickly realized the importance of genetic influences in the development of addiction — “Ignoring [the genetics] would ...

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Females more at genetic risk for developing insomnia than males, VCU study suggests

Genes may contribute more to the development of insomnia symptoms in females than in males, according to a new study led by a Virginia Commonwealth University graduate student.

Drawing on pre-existing data from the Virginia Adult Twin Studies of Psychiatric and Substance Use Disorders (VATSPSUD), a large data set collected by VCU psychiatry professor Kenneth S. Kendler, M.D., Mackenzie Lind found evidence that the heritability of insomnia could be higher for females than it is for males, suggesting ...

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VCU researchers and international partners are first to identify risk genes for clinical depression

For the first time in scientific history, researchers have identified specific genetic clues to the underlying etiology of clinical depression. The findings are the result of an international collaboration among researchers from Virginia Commonwealth University, the University of Oxford and throughout China to localize risk genes for major depressive disorder.

While prior studies have failed to identify replicated evidence for molecular genetic markers that predispose to risk for the disease, the international research team, in which VCU’s Virginia ...

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