Posts Tagged 'depression'

Genetic overlap between major depression and obesity in some patients

NEW YORK (Reuters Health) – Patients with major depressive disorder who experience increases in appetite, weight, or both have a higher genetic risk for obesity-related traits such as high body-mass index (BMI) and elevated levels of leptin and inflammation, researchers suggest.

“As clinicians, we are well aware that depression is highly heterogeneous, and patients with the same diagnosis of major depressive disorder may present with very different symptom profiles,” Dr. Yuri Milaneschi of VU University Medical Center Amsterdam in the Netherlands ...

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Featured Postdoc: Roseann Peterson, Ph.D.

Roseann Peterson, Ph.D. is a senior post-doctoral fellow at Virginia Institute for Psychiatric and Behavioral Genetics. Her interests in genetics began during her childhood. A deep curiosity about the natural world, first realized as a child during trips to her grandparents’ farm, led her to major in biology at the University of Minnesota (U of MN). During this time, she studied psychology as a second major. These interests converged when she took a behavioral ...

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The Genetic Underpinnings Of PTSD And Stress-Related Drinking

Dr. Ananda Amstadter, Ph.D. is Associate Professor in the Departments of Psychiatry, Psychology, and Human and Molecular Genetics. Her interests in the field of psychiatric genetics began when she worked as a research assistant during her undergraduate years. While coding archived assessments of women with borderline personality disorder, she was struck by the number of these women who had a history of trauma. These experiences launched her interest in traumatic stress psychopathology and ...

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Whole Genome Sequencing In Multiplex Families

Brien Riley, Ph.D. is Associate Professor in the Department of Psychiatry. He is a molecular geneticist interested in identifying genes that contribute to variation in the brain, central nervous system function, and psychiatric illness risk and behavior. These interests developed after he completed his bachelor’s degree in psychology, as a result of his dissatisfaction with the field’s way of approaching brain function and dysfunction. He was frustrated “because the field ...

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VCU and partners receive $5.7 million to continue transformative study of clinical depression

Virginia Commonwealth University is part of an international research team that has received a Wellcome Trust grant totaling more than $5.7 million to uncover the underlying biological processes that cause major depressive disorder. The study, to be conducted by researchers from VCU, the University of Oxford and throughout China, is an extension of a study from the same team that uncovered the first identified risk genes for clinical depression last year.

The design of the five-year study will replicate and extend ...

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VCU researchers and international partners are first to identify risk genes for clinical depression

For the first time in scientific history, researchers have identified specific genetic clues to the underlying etiology of clinical depression. The findings are the result of an international collaboration among researchers from Virginia Commonwealth University, the University of Oxford and throughout China to localize risk genes for major depressive disorder.

While prior studies have failed to identify replicated evidence for molecular genetic markers that predispose to risk for the disease, the international research team, in which VCU’s Virginia Institute for Psychiatric ...

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Unlocking the puzzle of anxiety and depression

A current Virginia Commonwealth University study hopes to begin unlocking the key to understanding anxiety and depressive syndromes – conditions that are known as internalizing disorders (IDs).

One in four people will suffer from an anxiety disorder in their lifetime, and between 15 and 20 percent of individuals will experience a depressive episode. Even with these high lifetime prevalence rates, very little is currently known regarding the genetic basis of IDs and how it relates to other internalizing risk factors.

John “Jack” ...

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