Multivariate Genetic Modeling
| Time | Speaker | Topic | Presentation | Notes/Examples |
|---|---|---|---|---|
| 09:00 – 10:00 | Kenneth Kendler | Statistical Genetics of Substance Use | Introduction | |
| 10:00 – 10:30 | Timothy York / Michael Neale | Review 1: R & OpenMx | Gen Epi Helper Functions R_Introduction.R |
|
| 11:00 – 12:30 | Hermine Maes / Elizabeth Prom | Review Multivariate Genetic Factor Analysis | ReviewMultivariatr Carey BG 1988 |
twinMulAceOrd.RselVATSma.dat twinCCCAceOrd.RselVATSird.dat |
| 01:30 – 02:30 | Nathan Gillespie / Brad Verhulst | Direction of Causation | DirectionOfCausation Lee 2012 Correlation-Causation Lee 2012 Commentary |
DOC_continuous.R |
| 03:00 – 04:00 | Michael Neale / Hermine Maes | Comorbidity | Comorbidity | altform.R bivariateBinaryACE.R bivariateBinaryACENoCon.R directionofCausation.R randomMultiformity.R threeDisorders.R readffpairs.R ffpairs.rec runAll.R comorbPlot.R |
Measurement & Phenotyping
| Time | Speaker | Topic | Presentation | Notes/Examples |
|---|---|---|---|---|
| 08:00 – 09:00 | Sarah Medland | Threshold Modeling | TuesdayMorning DataPreparation |
threshold.R thresholds twinAceBin-Traditional.R twinAceOrd-Traditional.R twinAceBin-FixE.R twinAceOrd-FixE.R twinAceOrd-FixThresholds.R two_cat.dat |
| 09:00 – 10:30 | Michael Neale / Shuanna Clark | Measurement Invariance / Underreporting | MeasurementInvariance | MIExample.R octomult_10aug2010.rdata |
| 11:00 – 12:30 | Ryne Estabrook / Nathan Gillespie | Factor Scores/ Item Response Model | FactorScoringAndIRT | factorScores.R fsData.txt transformFactorScores.R trueFactorScores |
| 01:30 – 03:30 | Shaunna Clark / Ryne Estabrook | Latent Class Analysis/Factor Mixture Model | Crosssectional_Mixture | Data_Oz_CAN_Sim.dat LCA_example.R LCA_2Classes.Rdata LCA_example_3c.R LCA_3Classes.Rdata LCA_example_4c.R LCA_4Classes.Rdata LCAdata.R |
Genes, Environment & Development
| Time | Speaker | Topic | Presentation | Notes/Examples |
|---|---|---|---|---|
| 08:00 – 09:00 | Sarah Medland | WednesdayMorning MatrixAlgebraHandout |
twinACE.R twinACECovSex.R twinACECovSexAge.R prepearlier |
|
| 09:00 – 10:30 | Mehta / Michael Neale | Hierarchical Mixed Modeling | ML-SEMinBehavioralGenetics | nLevelSEM-APracticalIntroduction |
| 11:00 – 12:30 | Nathan Gillespie / Lindon Eaves | Latent Growth Curve Modeling | LGC_modeling | LGC_ordinal.R LGC_continuous.R growth polychoricFunctionSim |
| 01:30 – 03:00 | Shuanna Clark / Ryne Estabrook | Growth Mixture Modeling, Regime Switching | GrowthMixtureModeling | GMM_example.R growth |
Family Processes
| Time | Speaker | Topic | Presentation | Notes/Examples |
|---|---|---|---|---|
| 08:00 – 09:00 | Sarah Medland | ThursdayMorning Ordinal |
twinACE.R twinAceOrd-FixThresholds.R |
|
| 09:00 – 10:00 | Lindon Eaves / Hermine Maes | Twin-Family and Extended Pedigrees | ExtendedTwinKishipDesigns AGESSiblingSpouseInteraction |
Siblings.R |
| 10:00 – 10:30 | Hermine Maes / Lindon Eaves | Nuclear Family, COT, ET | MLcorrelations ETdesigns |
Et88-P.R MZM DZM MZF DZF DZO ET88-P2.R ETdata.txt |
| 11:00 – 12:30 | Brad Verhulst / Sarah Medland | Sibling Models and Age Difference Moderation | ModeratingCovariance | TaSsim1.R TaSdata TaSmod.R ModGraph.R |
| 01:30 – 03:00 | Brad Verhulst | Building Models from Scratch | ACE example.R |
GxE Interaction
| Time | Speaker | Topic | Presentation | Notes/Examples |
|---|---|---|---|---|
| 08:00 – 09:00 | Sarah Medland | VCxEnvSimulatedSTUDENT.R GxEdata |
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| 09:00 – 10:30 | Lindon Eaves / Timothy York / Sarah Medland | Genotype Environment Interaction | GxE_Interaction Purcell_2002 Purcell & Sham_2002 Medland_2009 Nature Letter 2012 |
binaryGE.R GxEdata ordinalGE.R continuous_rGE.R binaryGE_CI_wrong.R badCIs binaryGE_CI_correct.R goodCIs |
| 11:00 – 12:30 | Tim Bates / Hermine Maes / Elizabeth Prom | Measured & Unmeasured GxE Interaction | SEM_Measured_Genotypes | UnivTwinACEGOrdExP.R selVATS.dat |
| 01:30 – 03:00 | Lindon Eaves / Michael Neale | Model Limitations | SummaryNIDA_AGES_Workshop | LCA_ExampleSeparateItemsPlanB.R |
