AGES Workshop – Oct. 26-30, 2015

Multivariate Genetic Modeling

Time Speaker Topic Presentation Notes/Examples
09:00 – 10:00 Kenneth S. Kendler Statistical Genetics of Substance Use (SU)/td> Introduction
10:00 – 10:30 Timothy P. York / Elizabeth Prom-Wormley Review 1: R & OpenMx R_intro
ACE_BMI.Rdata
ACE_BMI.Rmd
11:00 – 12:30 Hermine H. Maes / Timothy C. Bates Review 2: Genetic Factor Analysis Multivariate Sex Limitation MultivariateGeneticAnalysis twinMulSatAceCon.R
twinHetMulAceCon.R
usski.rec
01:30 – 03:00 Timothy Brick / Joshua N. Pritikin Fundamentals of Optimization & Model Fitting Optimization-OpenMxTwinWorkshop2015
opt.pdf
tour.R
03:30 – 05:00 Nathan A. Gillespie Direction of Causation & Comorbidity Models Mutualism, Sibling / Spousal Interaction DirectionOfCausation NU321_cannabis_psychosis.sav
Gillespie_DOC_modelling.R
polychoricMatrix3.R

Measurement & Phenotyping

Time Speaker Topic Presentation Notes/Examples
09:00 – 10:30 Cristopher R. Estabrook / Joshua Pritikin Sum & Factor Scores / Item Response Models FactorScoringAndIRT2015.pdf
pritikin-schmidt-20151022.pdf
factorScores2015Oct27.R
agesNICdata.txt
nsduh_small.csv
11:00 – 12:30 Michael C. Neale Measurement Invariance MeasurementInvariance getFactorScoresNew3.R
mi_modtest1.R
mitest_can.R
nsduh090913.txt
01:30 – 03:00 Michael D. Hunter Behavior Genetic Models in Multilevel Clothing MultilevelBG buildingBlocks.R
03:30 – 05:00 Timothy Brick Latent Class Analysis & Factor Mixture Model HeterogeneitySearch LCA-Basic.R
Data_Oz_CAN_Sim.dat
SEMtree-Basic.R
waisr-transformed.txt

Genes, Environment & Development

Time Speaker Topic Presentation Notes/Examples
09:00 – 10:30 Nathan A. Gillespie Latent Growth Curve Modeling Gillespie_Hunter_Wedneday.pdf
Gillespie&Eaves2015.pdf
DualChangeScore.R
simData.RData
11:00 – 12:30 Michael C. Neale Hierarchical Mixed Modeling RegimeSwitching.pdf
regimeSwitching2015SEM.pdf
GrowthMixtureModel_PathRaw.R
GrowthMixtureModel_MatrixRaw.R
RegimeSwitching_MatrixRaw
NoCholDifferentTransitions.R

RegimeSwitching_MatrixRaw
NoCholDifferentTransitionsAllFixed.R

nlsy.txt
01:30 – 03:30 Michael D. Hunter Hidden Markov & Latent Transition Models LatentTransitionHMM funcHMM.R
HmmLta.R
03:30 – 05:00 Steven M. Boker Dynamical Systems Models: Adaptive Equilibrium Regulation AGES-Boker-AER-151028.pdf AnalysisTest1-151017-d.R
Fourwells.mov
GLLA-Sim-AR1-151028.R
GLLA-Sim-DLO-151028.R
GLLA-Test1-151028.R
GLLAfunctions.R
LDE-Sim-AR1-151028.R
LDE-Sim-AR1-FitDLO-151028.R

Family Processes

Time Speaker Topic Presentation Notes/Examples
08:00 – 09:00 Timothy P. York Functions in R AGES2015Functions.R
09:00 – 10:30 Tim Bigdeli / Benjamin M. Neale Introduction to Modeling Genomewide Data Biometrical Model
11:00 – 12:30 Lindon J. Eaves Genetic Relationship Matrices Theory GCTA Maternal Effects
11:00 – 12:30 Brad Verhulst / Sarah Medland Sibling Models and Age Difference Moderation Kirkpatrick_AGES2015–mxGREML.pptx TaSsim1.R
CondenseSlotsDemo.R
AGES2015GRM.grm.id
AGES2015GRM.grm.bin
MAGES2015GRM.grm.N.bin
GREMLphenodata.csv
AGES2015FactorModGRM.grm.id
AGES2015FactorModGRM.grm.bin
AGES2015FactorModGRM.grm.N.bin
GREMLFactorModData.csv
03:30 – 05:00 Benjamin M. Neale SNP-based Heritability Estimating – Alternative Methods AGES_LDSC.pptx

GxE Interaction

Time Speaker Topic Presentation Notes/Examples
09:00 – 10:30 Bradley Verhulst Genotype Environment Interaction NIDA GxE
11:00 – 12:30 Timothy C. Bates Moderation of ACE in Twin Designs
01:30 – 03:00 Roseann Peterson / Benjamin M. Neale Mediation / Mendelian Randomization
03:30 – 05:00 Lindon J. Eaves Future Directions